GLP-1 Medications – FDA Guidance and Compounded Products
Not long ago, few outside the medical community had heard of semaglutide and tirzepatide—two drugs in the GLP-1 (glucagon-like peptide-1) receptor agonist class, approved for diabetes management. The medications work by decreasing caloric intake through mimicking the natural hormone GLP-1 normally released in the gut after eating. The GLP-1 agonists bind to receptors in the brain, pancreas and intestines, which helps to regulate insulin release, lower blood sugar levels, slow down digestion, and reduce appetite.
Read MoreFluoride in Drinking Water: 2025 and Beyond
In 1999, the Centers for Disease Control and Prevention (CDC) recognized the fluoridation of drinking water as one of the “ten greatest public health achievements of the 20th Century.” The practice has reportedly reduced tooth decay in children by 40-70% and tooth loss in adults by 40-60%.
Read MoreBiomarkers: Transforming Medicine
When Angela Haupt, a health and wellness editor at Time Magazine, had nearly two dozen vials of her blood drawn for a health startup, she received eight pages of clinical notes analyzing 105 personalized biomarkers. Did she receive valuable insights predictive of her future health, or an overload of indecipherable data? The answer is debatable. It may depend on who you ask, who is reading the information, and for what purpose. What is certain is that the use of biomarkers in the healthcare industry is expected to grow exponentially.
Read MoreThe Promise of mRNA Technology
Vaccines utilizing messenger ribonucleic acid (mRNA) technology have been in the news often the past few years, but mRNA vaccines have been under development since the 1990’s. The first clinical trial using ex-vivo human cells began in 2001. The first in-human vaccine trial was initiated in 2008.
Read MoreMass Tort Settlements & Life Science Litigations
Mass tort and class action settlements totaled over $40 billion for the third year in a row. While this number is staggering, unlocking its history provides key considerations to dial back this billion-dollar settlement trend. Mass tort litigation has been a part of the American legal system for decades. Settlements have been the end of a long road of bellwether trials, ultimately resolving the litigation.
Read MoreProbiotics in Live Biotherapeutics: Innovations and Hurdles
Probiotics are skyrocketing in popularity. While they are classified as dietary supplements, probiotics are often being marketed and used to treat symptoms and illnesses despite not having FDA approval, which can lead to safety concerns for consumers.
Read MoreNavigating Liability Protections for Life Science Companies Under Blood and Tissue Shield Laws
Beginning in the 1960s, medical facilities, blood banks, and other public providers of blood products began seeing limited statutory protections arise in most states through what has become known as “blood shield laws.”
Read MorePsychedelics & Psilocybin: Unlocking Therapeutic Potential
Psychedelic drugs have long fascinated humanity, from use in ancient rituals to potential therapeutic benefits. Among these, psilocybin, the active compound in "magic mushrooms," stands out for its historical significance and promising future. This article delves into the legal status, clinical trials, history, and future of psychedelic drugs, with a particular focus on psilocybin.
Read MoreExploring Genetic Testing Privacy: Safeguards and Concerns
Not so long ago, genetic testing was aspirational, a process more common to science fiction than accepted medical research. Over the past several decades, however, genetic testing and gene therapy have become mainstream.
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